Hydroxypropyl beta Cyclodextrin

Hydroxypropyl beta-cyclodextrin (HPBCD) is produced from beta-cyclodextrin (BCD) by addition of propylene oxide to some of the

Applications1.Improving the solubility of drugs.Insoluble drugs including Chinese herbal medicines might be turned into injections by the derivatives of cyclodextrins2.Inproving the bioavailability of drugs.For example,effectively control release oral dosing of injection of 5-fuorocarbamidopyrimidine might be prepared with an improved bioavailability,which might bring in a decreasing of the dosage but an increasing of the curative effect.On the other hand,an injection could be worked on the patients who haven't any go-aheadism.3.Adjusting or controlling the releasing of the drugs.For example,lasting effective dosings of VA,VE,VD,VK,testosterone and progesterone etc might be made with an improved stability.4.Decreasing the toxicities of the drugs.For example,to decrease the haemocylolysis of the drugs.The stimulating to eyes or nasal cavities of the related drugs cold also be decreased.5.Improving the stabilities of the drugs.For example,to prevent the volatilization,sublimation,oxidation decomposition etc.6. Concealing or rectifying the badness odor of testing.7.Inproving the synthesis effects as well as qualities of the drugs by chiral selective catalysis of cyclodextrin derivatives.It is very important for a chiral structure in drugs.8.Constructing stational chiral phases for the separation of isomers of drugs.9.Exploring molecular probes for examining differentiation of gene etc.10.Looking for new drugs or new coordination materials by more proper modifications of cyclodextrions.11.The recent work shows that HP beta CD etc could also accelerate the permeable absorption of the drugs of Testosterne etc.12.Cyclodextrin derivatives not only could play an important role in drugs and related field,but also could play an important role in cosmetics,foods and spices etc based on the structures of cyclodextrin derivatives.

Hydroxypropyl beta Cyclodextrin